Research

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Explore a curated selection of journal articles highlighting recent advances in Sickle Cell research. Click “Learn More” for clear, easy-to-understand explanations of each the findings and practical insights on how they can be applied to patient care, advocacy, or education.

The Modern Use of Hydroxyurea for Children with Sickle Cell


Quinn, Charles T, and Russell E Ware. “The modern use of hydroxyurea for children with sickle cell anemia.” Haematologica vol. 110,5 (2025): 1061-1073. doi:10.3324/haematol.2023.284633

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Nutraceuticals interventions in the management of sickle cell anemia


Saha, P., Jha, R., Yasmin, A. et al. Nutraceuticals interventions in the management of sickle cell anemia: bridging nutritional support and therapeutic strategies. Med Chem Res 34, 1631–1662 (2025). https://doi.org/10.1007/s00044-025-03445-x

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Stroke prevention in Hispanic children with sickle cell anemia


Nieves R, Latham T, Marte NM, et al. Stroke prevention in Hispanic children with sickle cell anemia: the SACRED trial. Blood Adv. 2025;9(8):1791-1800.

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Gene therapy in sickle cell anemia mice and human models


Shrestha, Archana et al. Molecular Therapy Methods & Clinical Development, Volume 33, Issue 2, 101439

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Dental caries prevention of children with and without sickle cell anaemia in Nigeria


Afolabi, J.B., Oziegbe, E.O., Adegoke, S.A. et al. Dental caries prevention profile of children with and without sickle cell anaemia in a suburban community in Nigeria. BMC Res Notes 18, 353 (2025). https://doi.org/10.1186/s13104-025-07418-6

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Managing emotional and physical stress in sickle cell anemia


Obeagu, Emmanuel Ifeanyi PhDa,*; Obeagu, Getrude Uzoma B. NScb. Managing emotional and physical stress in sickle cell anemia: a review of effective strategies and approaches. Annals of Medicine & Surgery 87(3):p 1370-1382, March 2025. | DOI: 10.1097/MS9.0000000000002748

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How Blood Flow in the Brain Differs in Children With and Without Sickle Cell Disease


Kinkunda, P. L., Nkodila, A. N., Mutamba, J. K., et al. Hemodynamic profile of cerebral arteries using transcranial Doppler in children with sickle cell disease compared to children without sickle cell disease: Prospective analytical study. BMC Pediatrics, 25(1), 246. https://doi.org/10.1186/s12887-025-05610-y 

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